NT-proBNP and BNP: levels increase during the first trimester, decrease in the second and third trimesters, and rise again during delivery. Values > 200 ng/L of NT-proBNP are associated with heart failure and hypertensive disorders in women with pre-existing heart conditions. High-sensitivity cardiac troponins remain unchanged in uncomplicated pregnancies but increase in conditions like hypertensive disorders and other cardiovascular complications. Troponins are proposed as risk assessment tools, though further validation is needed. The gene discussed is NPPB; the disease is hypertensive disorder.