Of the 343 patients initially assessed for eligibility, 69 were excluded based on pre-established criteria: monofollicular response (n = 20), ovarian endometrioma (n = 13), LH level < 2 IU/l (n = 9), body mass index (BMI) ≥ 30 kg/m2 (n = 18) and diagnosis of polycystic ovarian syndrome (PCOS) (n = 9). Here, PLOD1 is linked to polycystic ovary syndrome.