VEGFA and metastatic colorectal cancer: Supporting the potential functional relevance of this variant, Burgermeister et al. reported that in metastatic colorectal cancer patients receiving bevacizumab (an anti-VEGF therapy), the TT genotype of rs11022780 was associated with longer overall survival, whereas the C allele predicted poorer clinical outcomes (HR = 1.61, p = 0.014) [67].