Currently, type 1 diabetes remains incurable; nonetheless, the landscape for insulin administration has vastly changed in the last few decades, and treatment of type 1 diabetes has greatly improved with the emergence of new technological advancements such as continuous glucose monitoring [CGM], insulin pumps, and automated insulin delivery [AID] systems or hybrid closed-loop systems [11,12,13]. The gene discussed is INS; the disease is type 1 diabetes mellitus.