Consequently, the reduction in miR-21 expression effectively alleviates this suppression, enabling the upregulation of crucial tumor-suppressing and apoptosis-inducing proteins (PDCD4, PTEN, FASL, CASP genes, and p53), resulting in apoptosis, cell proliferation inhibition, and overall tumor growth suppression [162] (Table 3). Here, PTEN is linked to neoplasm.