Research revealed that PTS boosts the susceptibility of prostate cancer cells to NK cell-mediated cytotoxicity by upregulating MICA/B (MHC Class I Chain-Related Proteins A and B) expression, which are ligands for NKG2D, and reducing TGF-β1 secretion through the inhibition of miR-20a [202]. The gene discussed is MICA; the disease is prostate cancer.