RAGE/AGE, FGF-23, IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-6, MMP-2, MMP-7, TIMP-2, and TIMP-4 were significantly different between the ctrl and amyloidosis subgroups (p < 0.001, Figure 2A); ENRAGE/S100A12, MMP-13, and MMP-9 showed no significant difference. The gene discussed is AGER; the disease is amyloidosis.