Clinical studies also indicate that elevated Gal-3 concentration is associated with unfavourable in-hospital outcomes in ST-segment elevation MI (STEMI) and, moreover, is related to left ventricular (LV) remodelling, HF hospitalisation, and cardiovascular death in mid-term and long-term follow-up [14,15,16,17,18,19,20,21]. This evidence concerns the gene LGALS3 and hydrops fetalis.