To our knowledge, this study represents the first analysis of the identified genes (ABCG2, ABHD4, MOBKL1A, AK3, SDE2, PRAMEF4, CREM, CDH4, BRAT1, SDK1, NR3C2, ACTG1, COG5, CAT, HDAC4, FTO, DOK7, OCLN, and ATXN1) in the context of sleep and obesity-related DNA methylation changes in children. Here, CAT is linked to obesity disorder.