Focusing on the intersection of these two categories, we identified 10 genes, CDH4, NR3C2, ACTG1, COG5, CAT, HDAC4, FTO, DOK7, OCLN, and ATXN1 that were significantly differentially methylated between early and late bedtime groups and implicated in both sleep and obesity-related processes [Table S5]. The gene discussed is HDAC4; the disease is obesity disorder.