Focusing on the intersection of these two categories, we identified 10 genes, CDH4, NR3C2, ACTG1, COG5, CAT, HDAC4, FTO, DOK7, OCLN, and ATXN1 that were significantly differentially methylated between early and late bedtime groups and implicated in both sleep and obesity-related processes [Table S5]. This evidence concerns the gene CDH4 and obesity due to melanocortin 4 receptor deficiency.