As the information about these inflammatory and immunomodulatory factors in oral tissue pathologies like clefts is rather limited, the assessment of the NFκB p65 and CCL4 proteins and PTX3 gene in postnatal human cleft lip tissue could provide additional insight about the molecular processes and tissue homeostasis disturbances seen in human postnatal cleft lip tissue. The gene discussed is NFKB1; the disease is cleft lip.