NFKBIE and HIV infectious disease: The results revealed that HIV infection upregulated proteins that are associated with HIV-infected MDMs transitioning to a latent reservoir (e.g., NF-κB inhibitor epsilon (IκBε), MHC class I processing and antigen presentation, GABAergic and glutaminergic receptor signaling, and the neurotransmitter release cycle, whereas JWH-133 treatment inhibited these pathways.