In our results, approximately 67% of the patients were overweight or obese according to BMI, and it was observed that individuals with the risk allele A had a higher HC compared to those with the ancestral allele G. In the Indonesian population, the UCP2 rs660339 polymorphism was also associated with obesity and body fat distribution [26]. This evidence concerns the gene UCP2 and obesity due to melanocortin 4 receptor deficiency.