ICAM1 and laryngotracheoesophageal cleft: However, within the LC group, male patients (n = 50) exhibited significantly higher expression of several crucial endothelial factors compared to female patients (n = 13): E-Sel (p = 0.001), VCAM-1 (p = 0.004), and ICAM-1 (p = 0.01, Figure 4A); D-Dimer expression remained comparable between LC females and males (p = 0.61, Figure 4A).