Study group: 120 patients with cannabis allergy (CA) (confirmed by clinical history of allergy symptoms after cannabis exposure)Control group: 62 healthy individuals (HC) and 189 atopic individuals (90 pollen sensitized controls without nsLTP sensitization (P + LTP-); 99 pollen sensitized nsLTP sensitized controls(P + LTP+)). The gene discussed is SCP2; the disease is allergic disease.