Huang et al. substantiated these results by identifying ferroptosis-associated differentially expressed genes (DEGs) (ATF3, BNIP3, DDIT4, LPIN1, NOS2, NQO1, SLC2A1, SLC2A6) that are prominent in ROS metabolism and antioxidant pathways in PCOS granulosa cells [50]. This evidence concerns the gene ATF3 and polycystic ovary syndrome.