Huang et al. substantiated these results by identifying ferroptosis-associated differentially expressed genes (DEGs) (ATF3, BNIP3, DDIT4, LPIN1, NOS2, NQO1, SLC2A1, SLC2A6) that are prominent in ROS metabolism and antioxidant pathways in PCOS granulosa cells [50]. The gene discussed is DDIT4; the disease is polycystic ovary syndrome.