Analysis of methylation profiles combined with single-cell transcriptomes of nasal cells of COVID-19 patients showed that hypermethylation of ciliary function genes (e.g., FOXJ1, DNAH5) led to sustained transcriptional repression up to 12 months post-infection, while hypomethylation in immune genes (e.g., chemokine receptors) upregulated inflammatory pathways in monocyte-derived macrophages [31]. Here, DNAH5 is linked to infection.