Indeed, a registered clinical trial (NCT05241444), which is still recruiting patients, aims to test in 30 participants with IPEX syndrome the infusion of autologous CD4+ T cells, which have undergone lentiviral-mediated gene transfer of the healthy human FOXP3 gene [151]. This evidence concerns the gene FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.