RNA-seq analysis showed that lin-9 DREAM MuvB core complex component (Lin9), forkhead box M1 (FOXM1), and nuclear transcription factor Y subunit beta (NF-YB) expression were reduced by 7.002-, 7.36- and 4.27-fold, respectively, in HCC cells treated with HO-1197 compared with control cells. Here, FOXM1 is linked to hepatocellular carcinoma.