PRKG1 and cancer: Downregulated: Proximal tubule bicarbonate reclamation (KEGG: rno04964)—2 genes, FDR = 0.046; Hepatitis B (KEGG: rno05161)—3 genes, FDR = 0.024; Endocrine and other factor-regulated calcium reabsorption (KEGG: rno04961)—3 genes, FDR = 0.025; Morphine addiction (KEGG: rno05032)—4 genes, FDR = 0.014; Purine metabolism (KEGG: rno00230)—4 genes, FDR = 0.029; Gastric cancer (KEGG: rno05226)—4 genes, FDR = 0.044; cGMP–PKG signaling pathway (KEGG: rno04022)—4 genes, FDR = 0.046; Pathways in cancer (KEGG: rno05200)—7 genes, FDR = 0.046; Metabolic pathways (KEGG: rno01100)—13 genes, FDR = 0.046.