When stratified for BMI greater than 30 kg/m2 for both PCOS and controls (demographic data shown in Supplementary Table S2), there were no differences in BMI, CRP, insulin or Homeostasis model of assessment—insulin resistance (HOMA-IR), but the PCOS cohort had hyperandrogenemia with raised testosterone. The gene discussed is INS; the disease is polycystic ovary syndrome.