LEPR and mitochondrial DNA depletion syndrome 4a: Comparison of the LEPR mRNA level for the above-mentioned isoforms between chronic CHD and AHD patients revealed that LEPR1, LEPR2, LEPR2/2, LEPR3, LEPR3/2, LEPR4 expression in EAT of the chronic CHD group was 1.5-, 2.8-, 1.5-, 2.2-, 1.9-, and 2.1-fold lower, respectively, than that in the AHD group (p < 0.05).