Results: Gal-9, sTREM-1, and sCD25 could discriminate sepsis from NIOF (Gal-9, area under the curve [AUC], 0.599–0.678; sTREM-1, AUC, 0.616–0.695; sCD25, AUC, 0.710–0.781) and septic shock from sepsis (Gal-9, AUC, 0.562–0.667; sTREM-1, AUC, 0.572–0.676; sCD25, AUC, 0.555–0.660), respectively. This evidence concerns the gene LGALS9 and Sepsis.