CXCL8 and Cirrhosis: CXCR4 (AUC = 0.941), COL1A2 (AUC = 0.919), CCR7 (AUC = 0.878), COL1A1 (AUC = 0.853), CXCL12 (AUC = 0.848), and CXCL8 (AUC = 0.828) had similar AUC values (Figs 7A–F), demonstrating that the identified hub genes exhibited a reliable discriminatory capacity as potential biomarkers for cirrhosis.