Not only that, an analysis conducted on the primary tumors and lymph nodes of 271 NSCLC patients found that low proximity of PD‐1+TIM‐3−CD8+ tissue‐resident memory T (TRM2) cells to tumor cells was associated with the recurrence of early lung squamous cell carcinoma (LUSD), as well as the high proximity of PD‐1+TIM‐3+CD8+ TRM4 cells to tumor tissues implicated the increased recurrence of early lung adenocarcinoma (LUAD) [6]. This evidence concerns the gene CD8A and non-small cell lung carcinoma.