MUC2 and colitis: Interestingly, the gene expression levels of colonic mucin 2 (MUC2), the predominant mucin secreted in the colon and small intestine, were significantly higher in mice receiving preventive KE supplementation, but not in KD-fed mice, when compared to CD-fed controls in both DSS- and TNBS-induced colitis models (Fig. 6A , B, Supplementary Fig. S6A , B).