CD79A and infection: Lipid nanoparticle (LNP)-encapsulated mRNA (mRNA-LNP) vaccines encoding a PEDV multiepitope chimeric spike (Sm) protein (PEDV-S mRNA-LNP) have been demonstrated to activate CD4 + and CD8 + T cells and induce PEDV-specific IgG and IgA in the serum and colostrum of S-mRNA-immunized sows, which could be transferred to suckling neonatal piglets, providing protection against AH2012/12 infection (Kirchdoerfer et al., 2021; Zhao et al., 2024).