In pancreatic cancer, LINC00473 promotes PD-L1 expression by sponging miR-195-5p (Zhou et al., 2019), while in hepatocellular carcinoma, PCED1B-AS1 upregulates PD-L1 via miR-194-5p (Fan et al., 2021). This evidence concerns the gene CD274 and hepatocellular carcinoma.