This interaction suggests that MALAT1 might influence PD-L1 expression by guiding epigenetic modifications or by serving as a regulatory protein scaffold, although the precise mechanism in OSCC requires further investigation; (III) At the epitranscriptomic level, the N6-methyladenosine (m6A) writer protein METTL3 has been shown in pancreatic cancer to enhance MALAT1 stability. Here, MALAT1 is linked to pancreatic neoplasm.