CXCL13 and Cryptococcal meningitis: However, previous studies have not confirmed the ability of CSF-CXCL13, CSF-CXCL10, and CSF-CXCL8 to distinguish NS from other CNS (such as tuberculous meningitis and cryptococcal meningitis), and some research samples are too small (only a dozen cases), resulting in some bias in the results (8).