Similarly, activated microglia can also release chemokines such as CCL2, CXCL10, and CX3CL1, that can mediate the recruitment of additional inflammatory cells, including peripheral immune cells, to the site of infection, thereby amplifying the inflammatory response and associated neurotoxicity (Errede et al., 2022; Kinuthia et al., 2020). This evidence concerns the gene CCL2 and infection.