Specifically, the expression of ATG16L1 was positively associated with odds of preeclampsia (OR: 1.214, 95%CI=1.007-1.463, P-SMR=0.042, FDR-SMR=0.644) Subsequent colocalization analysis provided suggestive evidence (PPH4 > 0.5) that the association signals for 6 of these 29 genes likely share a common causal variant with the preeclampsia GWAS signal (Figure 2A). Here, ATG16L1 is linked to preeclampsia.