After NR6A1 was silenced or overexpressed in A549 cells, quantitative RT‒PCR revealed that interference with NR6A1 increased the expression of miR-302a, whereas overexpression of NR6A1 decreased the level of miR-302a, indicating that NR6A1 exerted transcriptional inhibition ontranscriptionally inhibited miR-302a in lung cancer cells (Fig. 5A). Here, NR6A1 is linked to lung cancer.