Further, activation of α7‐nAChRs with nicotine also causes further downregulation of epithelial markers, that is, E‐cadherin and β‐catenin, and upregulation of mesenchymal proteins, for example, fibronectin and vimentin, thereby advancing the advantage achieved during the occurrence of epithelial to mesenchymal transition (EMT) in NSCLC cells [34, 104]. Here, CHRNA7 is linked to non-small cell lung carcinoma.