F7L6 did not rescue the growth of tumor organoids derived from WT (non-HF7) MMTV-Wnt1 tumors, confirming selectivity of F7L6 for human FZD7 and hFzd7, but not WT Fzd7 (SI Appendix, Fig. S5). The gene discussed is WNT1; the disease is neoplasm.