MYH9 knockdown resulted in significantly lower infection levels of the New World arenavirus (NWA) Tacaribe (TCRV), the Old World arenavirus (OWA) Lymphocytic Choriomeningitis virus (LCMV), the flavivirus Zika (ZIKV), the rhabdovirus vesicular stomatitis virus (VSV), and the togavirus Mayaro (MAYV) (Fig. 1C), while infection levels of the retrovirus murine leukemia virus (MLV) were not reduced upon siMYH9 transfection with respect to a siRNA control (siCTRL) (Fig. 1D). The gene discussed is MYH9; the disease is infection.