This differential behavior correlated with fewer OVA-specific CD8+ T cells in tumors (Figure 4G) and circulation (Figure 4H) of Tlr4fl/flx Pdgfrb-Cre.ert2 mice, which were induced by vaccination/immunization not only at a distant site from the site of tumor inoculation (hind footpad vs. in-between the scapulae), but also at a separate time point (day −3 vs. day 0). This evidence concerns the gene MAPK3 and neoplasm.