To further explore the association between serum CA50, CA242, and SAA levels and PC prognosis, PC patients were divided into high- and low-expression groups using ROC cutoff values (CA50: 53.85 U/mL; CA242: 37.85 U/mL; SAA: 18.10 mg/L) (Table 7 and Figure 3). This evidence concerns the gene SAA1 and pachyonychia congenita.