Initial management of GD includes antithyroid drugs (ATDs), such as carbimazole and propylthiouracil (PTU), alongside symptomatic management with beta blockers for relief of adrenergic features of hyperthyroidism [8,9]. ATDs are generally well-tolerated, with the most common side effects being rash, urticaria and arthralgia [2]. It is also widely accepted that all ATDs can affect the liver in some way, given its important role in metabolising thyroid hormones [10]. The gene discussed is TG; the disease is urticaria.