Compared to the healthy controls or asymptomatic COVID-19 patients, ICU-admitted patients show increased concentrations of granulocyte colony-stimulating factor (G-CSF), chemokine (C-X-C Motif) ligand 10 (CXCL10), C—C motif chemokine ligand (CCL) 2, CCL3, and TNF which are hallmarks of the “cytokine storm” associated with severe COVID-19.93 This evidence concerns the gene TNF and COVID-19.