established organoids from tumor and normal colon tissues of colorectal cancer patients and performed scRNA‐seq.[230] They found that tumor‐derived organoids replicated the gene expression features of cancer cells in vivo (e.g., Wnt signaling gene AXIN2), while normal colon tissue‐derived organoids exhibited tumor‐like features (e.g., Wnt signaling gene WNT6). This evidence concerns the gene AXIN2 and neoplasm.