Compared to normal or adjacent non-tumor tissues, S100A8, CLEC12A, CASZ1, GPM6A, and FEZ1 were downregulated in tumor tissues, while YWHAZ, OTX1, OCIAD2, XPR1, SLC39A11, DNAH14, TNS4, XDH, and RHOV were upregulated (Fig. 9A-C). The gene discussed is CASZ1; the disease is neoplasm.