Due to the relationship identified between NKX3.1 (a gene relevant to treatment resistant prostate cancer) and UTY (epigenetic regulator with many responsibilities in male development) [138], this suggests that UTY could have some connection to developmental processes which enhance predisposition to prostate cancers or even impact the cell populations which form from healthy tissue during malignant transformation. The gene discussed is NKX3-1; the disease is prostate carcinoma.