UTY and cancer: UTY is part of a family of demethylases which regulate gene expression dynamically following various stimuli [134] and is the ChrY-encoded paralog of UTX [116, 134], it has been implicated in many cancers including carcinomas of the kidney [116], glioblastoma, leukemia, squamous-like pancreatic cancer, and non-small cell lung cancer [134, 137].