The cumulative incidence of CRC by the age of 30 years was found to be 0%–2.4% for MLH1, 0.4%–3.0% for MSH2/EPCAM, 0%–0.05% for MSH6, and 0.02%–0.1% for PMS2 in females. Here, EPCAM is linked to colorectal carcinoma.