There are differing opinions on whether to recommend screening for hepatoblastoma (abdominal palpation, abdominal ultrasound, and serum alpha-fetoprotein every 3–6 months until 5 years of age [9, 229] or every 2 years until the age of 7 years [220]), depending on whether the effectiveness of screening is supported by evidence. Here, AFP is linked to hepatoblastoma.