In addition, we identified genes associated with aggressive disease forms in CLL or other tumor entities, including serum- and glucocorticoid-inducible protein kinase 3 (SGK3), a regulator of the PI3K pathway23–25 and LIM domain only 7 (LMO7), which has been implicated in multiple cancer entities26. This evidence concerns the gene LMO7 and B-cell chronic lymphocytic leukemia.