Next, we analyzed expression of genes previously reported in SLE genome-wide associated studies (GWAS) (https://www.ebi.ac.uk/gwas/efotraits/MONDO_0007915) such as IFN-related genes like Irf5, Tyk2, Slc15a4, genes associated with antigen processing and presentation (Tap2, Psmb8, H2‐Ab1, H2‐Eb2), NF-κB regulators and ubiquitin-editing proteins (Tnfaip3, Tnip1, Ube2l3), B cell and Fc receptor signaling (Blk, Cdkn1b, Fcgr2b, Fcgr3), autophagy and vesicle trafficking (Atg5, Tmem39a, Clec16a, Wdfy4). The gene discussed is IRF5; the disease is systemic lupus erythematosus.