Intriguingly, five asthma loci showed a significantly higher effect on CRSwNP: 6q24.2 near PHACTR2 (ORCRSwNP = 1.14 [1.07–1.21]), 5q31.1 near TCF7 (ORCRSwNP = 1.11 [1.05–1.17]), 11q24.3 near ETS1 (ORCRSwNP = 1.12 [1.07–1.17]), 12q13.3 near STAT6 (ORCRSwNP = 1.09 [1.04–1.13]), and 17p12 near TTC19 (ORCRSwNP = 1.07 [1.04–1.11]). This evidence concerns the gene PHACTR2 and asthma.