The expression levels of Nlrp3, TNF-α, and IL-1β were significantly elevated in the PD + siRNA NC group compared with those in the CON + siRNA NC group, whereas they were decreased in the PD + si-Acvr1 group relative to those in the PD + siRNA NC group (Fig. 8G). The gene discussed is NLRP3; the disease is Parkinson disease.