MZT2B and non-small cell lung carcinoma: To evaluate the in vivo significance of MZT2B in NSCLC progression, we established subcutaneous xenograft models in nude mice using pNSCLC1 cells stably expressing either control shRNA (shC) or MZT2B knockdown shRNA (kdMZT2B-sh2, see Figs. 5 and 6).