PLCL1 and rheumatoid arthritis: Notably, in thyroid tissues, we identified a significant regulatory role for the gene PLCL1 in the comorbidities of both DeP (P = 4.29 × 10−6) and asthma/RA (Pasthma = 1.07 × 10−4 and PRA = 3.90 × 10−3).