Additionally, B cells (P = 3.7 × 10−48) and monocytes (P = 1.4 × 10−41) were involved in multiple trait pairs within the Blood/immune category (Fig S3 in S1 File), with mitochondrial DNA (mtDNA) from CD14 + monocytes closely associated with autoimmune diseases [78]. Here, CD14 is linked to autoimmune disease.