PTGS2 and cystic fibrosis: that were dominated by those related to neutrophil degranulation, neutrophil extracellular trap formation, cytokine production and signaling, and chemotaxis, and included critical drivers of CF airway inflammation such as CXCL8, CXCR1, CXCR2, TLR4, PTGS2, and IL1R2 (2).