It is worth noting that this study found that Model 3 (which includes age, COPD, PaO2/FiO2 ratio, WBC count, AST, ALB, lymphocyte count, D-dimer, SMAT4, SATL1, IMATL1, ACL1, with an AUC of 0.858) had higher accuracy in predicting the MICU admission compared to Model 1 (which includes COPD, heart failure, PaO2/FiO2 ratio, WBC count, lymphocyte count, ALB, D-dimer, with an AUC of 0.832) and the SOFA score (AUC = 0.706). This evidence concerns the gene ALB and chronic obstructive pulmonary disease.