VAB LR-DCIS AM, according to COMET, would represent 6.9% (8/116) of all VAB cancers with 2.6% (3/116) underdiagnosed cases: 2 pT1a-bN0 hormone receptor positive breast cancers and 1 HR-DCIS (Figure 2). Here, NR4A1 is linked to ductal breast carcinoma in situ.